https://www.selleckchem.com/pr....oducts/epz004777.htm
A copper-promoted oxidative cyanomethylation/ring-expansion of vinylcyclopropanes with α-C(sp3)-H bonds in alkyl nitriles is established for the generation of 1-cyanoethylated 3,4-dihydronaphthalenes. This cyanomethylation/ring-expansion involves a radical pathway and proceeds via cyanomethyl radical formation, radical addition and ring-expansion. This ring-expansion strategy offers a highly atom-economical route for the construction of nitrile-containing 3,4-dihydronaphthalenes, which can be transformed into other useful products und
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