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1) and positive predictive value (45.2%, CI 32.8-57.5) were found. Despite good specificity (93.6%, CI 91.6-95.7) the area under the receiving operator curve remained poor (54.7%, CI 51.8-57.6). Negative specific agreement (84.5%, CI 81.4-87. and negative predictive value (77.0%, CI 73.7-80.2) were acceptable. An elevated ABI is insufficient to serve as a true diagnostic proxy for MAC. Studies that have drawn conclusions on the association between MAC and cardiovascular disease, solely based on the ABI, are likely to underestimate the

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