https://www.selleckchem.com/pr....oducts/lanraplenib.h
We herein review these advances in disease and pathophysiologic understanding and the associated clinical crossroads through a typical case vignette in the critical care setting. Diffuse intrinsic pontine glioma (DIPG) is the most common brainstem cancer in childhood. This rapidly progressing brainstem glioma holds a very dismal prognosis with median survival of less than 1year. Despite extensive research, no significant therapeutic advancements have been made to improve overall survival in DIPG patients. Here, we used an orthotopic