https://www.selleckchem.com/pr....oducts/fingolimod.ht
Mechanistic studies revealed that confluency-dependent upregulation of G expression in OS cells is mediated by increased de novo biosynthesis, through a yet unknown mechanism. Expression of G in OS cell lines is highly variable and associated with increasing cell confluency in vitro. Strategies for selective upregulation of GD2 are needed to enable effective therapeutic targeting of this antigen in OS. Expression of GD2 in OS cell lines is highly variable and associated with increasing cell confluency in vitro. Strategies for selecti
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