https://www.selleckchem.com/pr....oducts/chloroquine.h
BACKGROUND Hypoxia-inducible angiogenic pathway involving hypoxia inducible factor-1 alpha (HIF-1α), vascular endothelial growth factor (VEGF) and tumour necrosis factor- alpha (TNF-α) may regulate several biological processes related to inflammation. The present study aimed to assess the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) HIF-1α, VEGF and TNF-α levels in generalized aggressive periodontitis (G-AgP). METHODS 20 G-AgP patients and 20 periodontally healthy individuals were included. G-AgP p