https://hsp-signal.com/index.p....hp/in-a-situation-st
Practical study indicated that miR-100-5p certain into the 3'-untranslated region (3'-UTR) of FOXO3 to control its transcription. Furthermore, overexpression of FOXO3 abolished the protective outcomes of miR-100-5p. Enriched miR-100-5p in hucMSC-exo suppressed FOXO3 expression to prevent NLRP3 inflammasome activation and suppress cytokine launch and, therefore, protected cardiomyocytes from H/R-induced pyroptosis and injury.Enrich
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