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It may be employed in the make of pharmaceutical medicines as a substitute way to obtain normal anti-oxidants.Background because of increasing prevalence of diabetic issues and associated endothelial disorder, this research was done to analyze the consequences of co-administration of adrenoceptor blockers (prazosin and propranolol) and glibenclamide on plasma biomarkers of endothelial functions in diabetic rats. Methods Experiments had been done on 35 male Wistar rats (170-200 g). These