https://www.selleckchem.com/pr....oducts/deutenzalutam
BACKGROUND Early single-cell RNA-seq (scRNA-seq) studies suggested that it was unusual to see more than one isoform being produced from a gene in a single cell, even when multiple isoforms were detected in matched bulk RNA-seq samples. However, these studies generally did not consider the impact of dropouts or isoform quantification errors, potentially confounding the results of these analyses. RESULTS In this study, we take a simulation based approach in which we explicitly account for dropouts and isoform quantification error