https://www.selleckchem.com/pr....oducts/curcumin-anal
Gene-editing experiments commonly elicit the error-prone non-homologous end joining for DNA double-strand break (DS repair. Microhomology-mediated end joining (MMEJ) can generate more predictable outcomes for functional genomic and somatic therapeutic applications. We compared three DSB repair prediction algorithms - MENTHU, inDelphi, and Lindel - in identifying MMEJ-repaired, homogeneous genotypes (PreMAs) in an independent dataset of 5,885 distinct Cas9-mediated mouse embryonic stem cell DSB repair events. MENTHU
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