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Treatment of Add in Adults Treatment of add in adults typically involves a combination of medications, life skills training and psychotherapy. Most patients respond well to stimulant drugs like methylphenidate (Ritalin) and amphetamines, like amphetamine lisdexamphetamine (Adderall) or extended-release mixed amphetamine salts (Adderall XR). Stimulants can increase heart rate and blood pressure. Non-stimulants, like bupropion and atomoxetine, can help to reduce ADHD symp