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The global impact of somatic structural variants (SSVs) on gene expression in pediatric brain tumors has not been thoroughly characterised. Here, using whole-genome and RNA sequencing from 854 tumors of more than 30 different types from the Children's Brain Tumor Tissue Consortium, we report the altered expression of hundreds of genes in association with the presence of nearby SSV breakpoints. SSV-mediated expression changes involve gene fusions, altered cis-regulation, or gene disruption. SSVs considerably extend the numbers of patien

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What Is Audi Comfort Key? Audi comfort key is a game changer for many people. It makes it easier to search pockets and bags for keys to the car which can be a major trouble when carrying groceries, or sagely fastening children into their carseats. This technology is built on proximity sensors in the door lids and trunk that are connected to radio pulse generators within the key. Let's explore what makes this feature so useful. Keyless Entry There aren't many things more frustrating than having your car key disa