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OBJECTIVE The purpose of this report is to present the neuroendocrine phenotype of CEI, identify potential ligands, and determine the effect of specific treatment. DESIGN We have actually characterized gonadotropin pulsatility and followed this patient's endocrine profile and bone denseness over 8 many years. Seventy-five different substances had been tested for transactivation regarding the variation receptor. A personalized medicine strategy had been tailored to t