https://www.selleckchem.com/pr....oducts/Metformin-hyd
Background Insomnia is one of the most common nonmotor features of Parkinson's disease (PD). However, there are few practical guidelines for providers on how to best evaluate and treat this problem. Methods and Findings This review was developed to provide clinicians with a pragmatic approach to assessing and managing insomnia in PD. Recommendations were based on literature review and expert opinion. We addressed the following topics in this review prevalence of insomnia in PD, sleep-wake mechanisms, theoreti
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