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From June 2013 to June 2018, patients suffering from Asian giant hornet stings were treated with renal replacement therapy (RRT) in our hospital. We analysed the efficacy of different modalities of RRT in these patients. A comprehensive clinical history was recorded and a complete physical examination was done for each patient. Three different treatment plans were used in these patients according to the acute physiology and chronic health evaluation (APACHE) II score. These were (i) haemoperfusion (HP) and intermittent haemodialysis (IHD