https://www.selleckchem.com/pr....oducts/sgc-cbp30.htm
In terms of molecular genetics, high PRDM16 expression was significantly associated with a lower rate of CEBPA mutation ( = 0.01) and a higher rate of FLT3-ITD and DNMT3A mutation ( = 0.032 and = 0.004, respectively). In addition, PRDM16 expression was significantly correlated with WT1 expression in CN-AML ( = 0.7, 0.001). These data suggested PRDM16 expression could be used to predict the outcome of patients with CN-AML. PRDM16 is significantly associated with FLT3-ITD and DNMT3A mutation and WT1 expression and serves as a pote
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