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Similarly, axonal and other neuronal injuries in the HPC+MCAO group were also ameliorated. In the in vitro experiments, mild HPC significantly enhanced the viability of NSCs, promoted the migration of differentiated cells, and reduced apoptosis. Our results showed that HPC significantly promotes neurogenesis after MCAO and ameliorates neuronal injury. Our results showed that HPC significantly promotes neurogenesis after MCAO and ameliorates neuronal injury. Dichloroacetic acid (DCA), a by-product of disinfection in drinking water, is a