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43) and the ASCVD (r =0.5 scores, while the change in total cholesterol was the main determinant of the change in risk for the UKPDS-CHD (r =0.34). A significant correlation was identified between changes in temperature and changes in SBP (ρ=0.130, p=0.008), but not in other risk factors. Seasonal variations in the classic CVD risk factors influence the risk estimated using validated calculators. Seasonal variations in the classic CVD risk factors influence the risk estimated using validated calculators. It has been demonstrated that
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