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The evolutionary healing phenomenon of fractured tibia bone was investigated by comparing the bio-mechanical response of the human tibia following fracture fixation for two ranges of patient ages, when a body weight pressure (BWP) is applied. Three-dimensional finite element models have been developed by adopting the biomechanical characteristics of cortical and trabecular tibia bones, and considering the time-varying callus properties during the healing process for the two patients. The stress and strain levels generated within the fra