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Five days after surgery, irregular liver features took place association with PVT development in cirrhosis. Both coagulation and thromboelastography variables revealed that cirrhosis-PVT pigs exhibited a procoagulant condition through hyperfunction of platelets and clotting factors. Interleukin 6 (IL-6) as a possible inflammatory marker stimulated PVT-mediated infection activation in cirrhosis. Conclusions Our research provides in vivo research that