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This study aimed to explore the function of modified Yuejuwan (MYJ) on THP-1 macrophage-derived foam cells. First, human THP-cells were obtained, and then, grouping was made to the following control group, foaming group, foaming group +0.2 mg/mL Jiawei Yueju pill, foaming group +0.5 mg/mL Jiawei Yueju pill, and foaming group +1 mg/mL Jiawei Yueju pill. An Oil Red O staining assay was used to examine the uptake of oxidatively modified low-density lipoprotein (oxLDL). The secretion of interleukin (IL)-1 and tumor necrosis factor (TNF)- wer