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Our findings may open the way to unique nanofluidic functionalities, such as energy harvesting/storage and controlling transport at single-molecule and ion levels using the liquid layer near the wall.Ab initio CCSD(T)-F12/cc-pVTZ-f12//ωB97X-D/6-311G(d,p) + ZPE[ωB97X-D/6-311G(d,p)] calculations were carried out to unravel the area of the C5H7 potential energy surface accessed by the reaction of the methylidyne radical with 1-butyne. The results were utilized in Rice-Ramsperger-Kassel-Marcus calculations of the product branching ratios a