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Nevertheless, since the maturation of another VAC localizing protease, cathepsin protease B (CP, is dependent on CPL, it remained unidentified whether these problems happen right from ablation of CPL or indirectly from a lack of CPB maturation. Likewise, although a previously explained cathepsin D-like aspartyl protease 1 (ASP1) may possibly also may play a role in proteolysis, its definitive residence and function when you look at the Toxoplasma endolysosomal system weren't really defined. Right her