https://www.selleckchem.com/pr....oducts/cobimetinib-g
In orthodontic patients submitted to oral hygiene instruction, what is the efficacy of orthodontic toothbrush (O-T versus conventional toothbrush (C-T on plaque and gingival index reduction in randomized and non-randomized controlled clinical trials? Electronic database search was performed on PubMed, ClinicalTrials.gov, Cochrane Library and Google Scholar. Database research, study selection, data extraction and ROBINS-I and Risk of Bias Tool 2.0 analysis were conducted by two independently examiners in duplicate

https://www.selleckchem.com/pr....oducts/BIRB-796-(Dor
A total of 160 patients were included. The median vancomycin dose was 12.6 mg/kg with a trough of 24.6 mcg/mL. Weight, 24-hour UOP, vancomycin dose (mg/kg), and dialysate rate (mL/kg/h) were all determined to be independent predictors of vancomycin trough level. Patients who received 10 mg/kg doses of vancomycin (N=18) achieved a median trough of 21.5 mcg/mL, with 83% being therapuetic. In patients who received 10 mg/kg (N=142), the median trough was 25.5 mcg/mL, with 47% being therapeutic. Vancomycin dose, dialys