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How to Choose the Best ADHD Medication for Adults With Anxiety and Depression When a person suffers from both ADHD and anxiety or depression, treating the first disorder can improve the other. Mental health specialists prescribe antidepressants, stimulants for depression or antidepressants, along with ADHD medication. Wellbutrin (bupropion) and Effexor, (venlafaxine), are the two most commonly used antidepressants prescribed to treat