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Although the production of ROS generated by e-cigarettes is comparatively lower than ROS generated by conventional cigarettes, EPFRs in e-cigarettes appear to be more potent than those in tobacco TPM with respect to hydroxyl radical generation yield per unit EPFR. EPFRs in e-cigarette TPM may be a potential source of health impacts.Chain elongation is a process that produces medium chain fatty acids (MCFAs) such as caproic acid which is one of the promising products of carboxylate platform. This study analyzed the impact of bioaugmenta