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Numerous units of practices and strategies, including dermatoscopical examination of the "ABCDE" signs of the lesion, imaging methods or microscopical, immunohistochemical and serological biomarkers can be found and made use of today to diagnose malignant melanoma. Up to now, different biomarkers were proposed for melanoma, but only some, including circulating proteins, such lactate dehydrogenase, molecular and metabolite biomarkers, reach clinical applications. Gangliosides repr