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l is defined as 'any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcome' by the World Health Organization (WHO). Because this study is not a clinical trial, trial registration is not needed. Clinical trial is defined as 'any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcome' by the World Health Organization (WHO). Becau

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