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Blocking the PI3K/Akt pathway by Ly294002 inhibited HK2 activities, aerobic glycolysis, and cell proliferation in FoxA2-knockdown cells. Therefore, FoxA2 plays an important role in the proliferation and inhibition of HPCs by suppressing PI3K/Akt/HK2-regulated aerobic glycolysis.Purpose The sclera plays an important role in the biomechanical stability of the eye. We aimed to examine if changes in the shape of the anterior sclera occur in response to accommodation and convergence. Methods Thirty-six healthy young adult participants aged bet