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There was a significant decrease in cathelicidin after three months of treatment with combined NB-UVB phototherapy with methotrexate (p less then .01).Conclusion This study could contribute to the hypothesis considering the role of cathelicidin and vitamin D in the pathogenesis of psoriasis. The combined NB-UVB phototherapy with methotrexate had the highest clinical improvement of psoriasis vulgaris.HCV co-infection is widespread among people living with HIV who use drugs (PLHWUD). However, HCV testing was inconsistently impleme