https://www.selleckchem.com/pr....oducts/bromopyruvic-
Sleep deprivation induces systemic inflammation that may contribute to stress vulnerability and other pathologies. We tested the hypothesis that immunization with heat-killed Mycobacterium vaccae NCTC 11659 (MV), an environmental bacterium with immunoregulatory and anti-inflammatory properties, prevents the negative impacts of five days of sleep disruption on stress-induced changes in sleep, behavior, and physiology in mice. In a 2x2x2 experimental design, male C57BL/6N mice were given injections of either MV or vehicle on day