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ADHD Treatment For Adults The stimulants methylphenidate and amphetamine can boost the levels of certain brain chemicals. Nonstimulants, such as atomoxetine and antidepressants, work more slowly than stimulants but they can be beneficial too. of conditions can affect the response to ADHD medication. Doctors should treat the most severe symptom of any comorbid disorder first, and then check to see if the ADHD symptoms improve. Medication Adults with ADHD are typica