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97, confidence interval [CI] 95% -5.56 -2.38, p less then 0.001), discharge from ED (β = -3.94, CI 95% -5.97 -1.90, p less then 0.001), and discharge from hospital (β = -4.93, CI 95% -7.68 -2.18, p = 0.01). FI was positively associated with delirium (β = 3.68, CI 95% 1.53-5.83, p less then 0.01). Conclusion Higher frailty at ED admission was associated with lower hand grip strength and delirium during hospitalization in Mexican older adults.As a member of the M1 family of aminopeptidases, insulin regulated aminopeptidase (IRAP) is char