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tor of persisting high grade histology. However, this sensitivity came at the expense of specificity (52%, 95% confidence interval 45, 58%). A co-test of high risk human papillomavirus positivity or high grade cytology at 12 months, provided a high sensitivity (97%, 95% confidence interval 90, 99%), but low specificity (51%, 95% confidence interval 45, 58%). CONCLUSION Colposcopy and cytology are limited in their ability to exclude persistent high grade abnormality for young women undergoing observational management for cervical int

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2) and Cu/ZnSOD, thus suggesting their occurrence as cytoplasmic proteins. No FeSOD homologs were identified in Chroococcidiopsis sp. CCMEE 029, a feature that might contribute to its desiccation tolerance since iron produces hydroxyl radical via the Fenton reaction. The overall-overexpression in response to desiccation of the three identified SOD-coding genes highlighted the role of SODs in the antioxidant enzymatic defense of this anhydrobiotic cyanobacterium. The periplasmic MnSOD protected the cell envelope against oxidative damage,