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RESULTS Radiomics signature consisting of 12 selected features was significantly correlated with bone status (P less then 0.001 for both training and validation sets). The radiomics nomogram combined a radiomics signature from multiparametric MR images with independent clinic risk factors. The model showed good discrimination and calibration in the training cohort (AUC 0.93, 95% CI, 0.86 to 0.99) and the validation cohort (AUC 0.92, 95% CI, 0.84 to 0.99). DCA also demonstrated the clinical use of the radiomics model. CONCLUSION The radiomi