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Best Medication For ADHD The majority of ADHD treatment plans include medications. Finding and medication will take time. Be patient and open with your GP or a specialist. Stimulants work by increasing levels of chemicals in the brain that help control behavior. They are available in short-acting as well as long-acting versions. Short-acting medications are at their peak in a few hours and are typically taken 3-4 times per day. Long-acting medication lasts between 8 and 12 hours and is usually taken only once a day. Stimulants Adults aren't likely t