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© 2020 Wiley Periodicals, Inc.We describe two adolescent patients with pyoderma gangrenosum (PG) involving the face. Subsequent gastrointestinal evaluation revealed microscopic bowel inflammation suggestive of inflammatory bowel disease. While PG is rarely localized to the face, this brief report reveals two cases of pediatric facial PG and suggests a correlation between facial PG and microscopic colitis. © 2020 Wiley Periodicals LLC.OBJECTIVE Genome sequencing (GS) is promising for unsolved leukodystrophies, but its efficacy has not
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