https://www.selleckchem.com/pr....oducts/epz011989.htm
a single transcript makes the potential sheep TRD chain much larger than any known TR chain repertoire. The sheep genome, as the bovine genome, contains a large and diverse repertoire of TRA and TRD genes when compared to the "γδ T cell low" species genomes. The composition and length of the rearranged CDR3 in TRD V-delta domains influence the three-dimensional configuration of the antigen-combining site thus suggesting that in ruminants, γδ T cells play a more important and specific role in immune recognition. The sheep genome, as th
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