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Two commercial chimeric antigen receptor (CAR) T cell products, axicabtagene-ciloleucel (Yescarta®) and tisagenlecleucel (Kymriah®), are registered for the treatment of B cell neoplasia, for which an increased supply of CAR T cell products is required. The production of patient-specific CAR T cells as advanced therapy medicinal products (ATMPs) poses considerable challenges with respect to logistics, regulation, and manufacturing. Review of the CAR Tcell manufacturing process and the regulatory network, the current ch

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Bi Fold Repairs - How to Properly Maintain and Repair Your Bi Fold Doors Many bi-fold doors can become difficult to open, and some may even start to let in drafts. This is usually due to the hardware slipping out of alignment with time. Getting your bi-fold doors back in line is usually pretty simple. All it takes is a few minor adjustments. Misalignment Bi fold doors are beautiful homes, offering a wide range of benefits, including seamless indoor-outdoor integration as well as increase