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We introduce our horrible experience of lateral semicircular canal exposure due to unintended drilling during left facial nerve decompression. Nearly half of the canal was drilled-out, however, the membranous labyrinth was preserved and the defect was covered with temporal fascia. Immediately after surgery, the patient complained of vertigo with right beating nystagmus. However, the patient could hear an audible tuning fork sound and the Weber-test showed left-sided deviation. The vertigo gradually subsided and the facial palsy was

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In slightly more aggressive conditions, we observed transient accumulation of a decamer-of-dimers and appearance of 90-dimer capsids. In conditions where there is measurable kinetic trapping, we found that a highly diverse early intermediates accumulated within a fraction of a second and propagated into long-lived kinetically trapped states (≧90-mer). In all cases, intermediates between 35 and 90 subunits did not accumulate. These results are consistent with the presence of low barrier paths that connect early and late intermediates an