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In peripheral blood, CD19+ B lymphocyte levels clearly decreased whileCD3+ CD8+ T and CD3+ CD4+ T lymphocyte levels temporarily decreased butsubsequently increased. These results demonstrate that H1N1 in thelungs could reach lymphoid organs, inducethe depletion of B and T lymphocytes in peripheral blood and lymphoid organs, and suppress adaptive immunity.Objectives We aimed to isolate and identify bioactive molecules from Morus alba (Moraceae) leaves having arginase inhibitory activity towards the combat of clinical outcomes related to e