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At the end of study, infarct size and percentage of the area at risk were determined. We found that SD increased LVDP and RPP, while reducing the myocardial infarct size. Moreover, sympathectomy reversed SD induced reduction in infarct size and showed no differences as compared to IR. This study shows cardioprotective effects of acute sleep deprivation, which can be abolished by chemical sympathectomy in isolated hearts of rats. This study shows cardioprotective effects of acute sleep deprivation, which can be abolished by chemical sym
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