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Analyses of the expression of IHC markers were attempted between the PBC and their corresponding synchronous MALN and classified as concordant or discordant. Results were subjected to statistical analysis. Results Substantial agreement was observed for biomarker ER, PR, HER2/neu, p53, and Ki67 expression between PBC and MALN with k-value 0.79, 0.75, 0.89, 0.7, and 0.6, respectively. Conclusion There was high concordance for the IHC markers ER, PR, HER2/neu, p53, and Ki67 expression in matched pairs of PBC and corresponding synchronous MA