https://www.selleckchem.com/products/eg-011.html
ay be useful for detecting patient subgroups with enhanced placebo responses that can diminish assay sensitivity in pain clinical trials. High mobility group box 1 protein (HMGB1) is increasingly regarded as an important player in the spinal regulation of chronic pain. Although it has been reported that HMGB1 induces spinal glial activation in a Toll-like receptor (TLR)4-dependent fashion, the aspect of sexual dimorphisms has not been thoroughly addressed. Here, we examined whether the action of TLR4-activating, partially reduced disulfi
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