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The aim of this study was to compare the efficacy and safety of fractional carbon dioxide (CO ) laser versus carboxytherapy in treatment of striae distensae. This study was conducted on forty female patients with striae distensae on the abdomen. Patients were selected and divided randomly into two matched groups; group I was treated with fractional CO laser resurfacing and group II with carboxytherapy. Assessment and evaluation of the results were done by comparing photographs and the Global Aesthetic Improvement Scale (GAIS). Pregnancy, ob
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