https://fak-signal.com/afteref....fect-of-aflibercept-
For the 91-min scan duration, the influx constant K1 increased by 40.7% as well as the level of circulation (VT) by 30.4per cent after P-gp inhibition, although the efflux constant k2 failed to change significantly. Similar modifications were discovered for several assessed scan durations. K1 didn't rely on scan length (10 min-K1 = 0.2191 vs 91 min-K1 = 0.2258), while VT and k2 did. A scan length of 10 min appears sufficient to properly evaluate the P-gp pu
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