https://www.selleckchem.com/pr....oducts/sodium-l-lact
8492, p 0.0001). The SARS-CoV-2 detection rate by direct RT-qPCR was 95.8 % for Ct values 35. All negative samples were characterized by low viral loads (Ct 35) and/or long storage times before sample processing. Direct RT-qPCR is a suitable alternative to classical RNA RT-qPCR, provided that only fresh samples (storage 1 week) are used. RNA extraction should be considered if samples have longer storage times or if PCR inhibition is observed. In summary, this protocol is fast, inexpensive and suitable for all r

https://www.selleckchem.com/pr....oducts/gsk3326595-ep
Estimating excess mortality is challenging. The metric depends on the expected mortality level, which can differ based on given choices, such as the method and the time series length used to estimate the baseline. However, these choices are often arbitrary, and are not subject to any sensitivity analysis. We bring to light the importance of carefully choosing the inputs and methods used to estimate excess mortality. Drawing on data from 26 countries, we investigate how sensitive excess mortality is to the choice of the mort