https://www.selleckchem.com/GSK-3.html
https://www.selleckchem.com/GSK-3.html
Phospholipid N-methyltransferases generate various methylated phosphatidylethanolamine derivatives in thermophilic germs. We describe here design, synthesis, and biological evaluation of a series of highly potent HIV-1 protease inhibitors containing stereochemically defined and unprecedented tricyclic furanofuran derivatives as P2 ligands in combination with a variety of sulfonamide derivatives as P2' ligands. These inhibitors were designed to enhance the ligand-backbone binding and van der Waals intera
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