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First Line Treatment For ADHD in Adults Some people with ADHD find medication helps to manage their symptoms. Drugs like methylphenidate and amphetamine help by enhancing brain activity in the areas that control attention and behavior. Other medications, like the non-stimulant atomoxetine, and other antidepressants, perform differently but are equally effective. Regular visits to the GP are recommended for those who take medication. They can alter dosages and observe body