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There was a slightly increased risk of respiratory and urinary tract infections treated in primary care among secukinumab users compared to ustekinumab users (HR 1.22, 95% CI 1.03-1.43). Non-significant differences in estimated risk of severe respiratory and urinary tract infections (HR 0.96, 95% CI 0.57-1.61) and candidiasis (HR 1.80, 95% CI 0.84-3.84) treated in the hospital setting were observed. We observed a slightly increased risk of respiratory and urinary tract infections treated in primary care among secukinumab users compared