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39 [0.54]) and decrease in TFPI (-0.21 [0.50] free TFPI, -0.24 [0.22] TFPI activity -0.22 [0.20] total TFPI). However, HT induced prothrombotic change in biomarkers did not increase risk of VT. Women with prothrombotic levels of APC resistance and TFPI at baseline were not at increased risk of VT when randomized to HT compared with placebo. This suggests that testing for these biomarkers before starting HT is not required. HT led to prothrombotic change in these biomarkers after one year, but this did not relate to increased risk of VT. Wom
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